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KMID : 1143620180220010015
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Korean Journal of Nuclear Medicine Technology
2018 Volume.22 No. 1 p.15 ~ p.22
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Evaluation of MR Based Respiratory Motion Correction Technique in Liver PET/MRI Study
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Do Yong-Ho
Lee Hong-Jae
Kim Jin-Eui
Noh Kyeong-Woon
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Abstract
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Purpose: Respiratory motion during PET/MRI acquisition may result in image blurring and error in measurement for volume and quantification of lesion. The aim of this study was to evaluate changes of quantitative accuracy, tumor size and image quality by applying MR based respiratory motion correction technique (MBRMCT) using integrated PET/MR scanner.
Materials and Methods : Data of 30 patients (aged 62.5 ± 10.2 y) underwent 18F-FDG liver PET/MR (Biograph mMR 3.0T, Siemens) study were collected. PET listmode data for 7 minutes was simultaneously acquired with maximum average gate (MAG), minimum time gate (MTG) and non gate (NG) T1 weighted MR images. Gated PET reconstruction was performed using mu-maps generated from MAG and MTG by setting 35% of efficiency window. Maximum SUV (SUVmax),
peak SUV (SUVpeak), tumor size and full width at half maximum (FWHM) in the z-axis direction of MAG, MTG
and NG PET images were evaluated.
Results : Compared to NG, mean SUVmax and SUVpeak were increased in MAG 13.15%(p<0.0001), 8.66%(p<0.0001), MTG
13.27%(p<0.0001), 8.80%(p<0.0001) and mean tumor size and FWHM were decreased in MAG 14.47%(p<0.0001), 15.49%(p=0.0004), MTG 14.89%(p<0.0001), 15.79%(p=0.0003) respectively. Mean SUVmax and SUVpeak of MTG were increased by 0.07%(p=0.8802), 0.13%(p=0.7766). Mean tumor size and FWHM of MTG were decreased by 0.49%(p=0.2786), 0.36%(p=0.2488) compared to MAG. There was no statistically significant difference between MAG and MTG which increase total scan time for about 7 and 2 minutes.
Conclusion : SUV, accuracy of tumor size and spatial resolution were improved in both of MAG and MTG by applying
MBRMCT without installing additional hardware in liver PET/MR study. More accurate information can be provided with the increase of 2 minutes scan time if applying MTG of MBRMCT to various abdominal PET/MR studies affected by respiratory motion.
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KEYWORD
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Respiratory motion correction, PET/MR, SUV, Liver cancer
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